- Docente: Barbara Mantovani
- Credits: 5
- SSD: BIO/05
- Language: English
- Teaching Mode: Traditional lectures
- Campus: Bologna
- Corso: Second cycle degree programme (LS) in Bioinformatics (cod. 0443)
Course contents
Mutations. Polymorphic and parsimonious sites. Genetic distance elaborations. Model test and substitution models. Bootstrap evaluations. Selection, genetic drift, molecular drive, neutralism: protein coding genes, non protein coding genes, repeated elements. Dendrograms and networks. Rooting a tree. Methods: Neighbor Joining, Maximum Parsimony, Maximum Likelihood, bayesian (softwares: MEGA 3, PHYLIP, PAUP*, MRBAYES). Shimodaira-Hasegawa test; Molecular clock: two cluster test, branch length test and –ln Likelihood comparison.
Teaching methods
computer lab
Teaching tools
computer lab
Office hours
See the website of Barbara Mantovani